Director, Oligo-Bioconjugate Delivery

Company: Proclinical Group
Location: Boston
Posted on: November 1, 2024

Job Description:

Director, Oligo-Bioconjugate Delivery - Permanent - Boston, MAProclinical is seeking a Director of Oligo-Bioconjugate Delivery to lead a cross-functional group focused on advancing tissue targeted biotherapeutics, particularly oligonucleotide conjugates. This is an exciting opportunity to shape a strategy for therapeutic development and contribute to a growing pipeline.Primary Responsibilities:

• Lead the development and optimization of oligonucleotides and linker/conjugation chemistries for tissue targeted delivery.
• Develop and implement strategies to support the engineering, production, and characterization of oligonucleotide bioconjugates.
• Design and build lab space to meet the needs of the Oligonucleotide Chemistry & Bioconjugation group.
• Recruit and mentor a team of scientists to discover and develop candidate bioconjugates.
• Contribute to the growth of the non-viral pipeline by achieving platform and program goals.
• Establish a network of external partners, including academic institutions and CROs, to enhance capabilities.
• Stay updated on technological advancements in the oligonucleotide/ADC space.
• Develop and manage timelines, resources, and operating budgets.Skills & Requirements:
  • Expertise in biochemistry, protein engineering, chemical engineering, or a related field.
  • Proven leadership experience with a track record of building and growing cross-functional teams.
  • Deep knowledge of conjugation and oligonucleotide chemistries, and analytical characterization techniques.
  • Success in the discovery, characterization, and development of bioconjugation-based therapeutics.
  • Experience managing CROs for the production and characterization of bioconjugates.
  • Strong analytical, research, and organizational skills.
  • Self-motivated with the ability to handle multiple projects and meet deadlines.
  • Excellent oral and written communication skills.
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Keywords: Proclinical Group, Arlington , Director, Oligo-Bioconjugate Delivery, Executive , Boston, Massachusetts