Senior Staff Engineer, Modeling

Company: Takeda Pharmaceutical
Location: Lexington
Posted on: October 16, 2024

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Senior Staff Engineer, Modeling - where you will be part of a patient-focused company that will inspire and support your career. You will also support process development and optimization of production processes for biopharmaceuticals through modeling approaches for use in manufacturing facilities. As part of the Advanced Technologies Group within Biologics Process and Product Development, you will report to Head, BPD Data and Modeling Applications.How you will contribute:

• Mechanistic modeling of upstream and downstream processes with simulation software applications to enhance model-based process development.
• Modeling of process sustainability and economics of new or improved biopharmaceutical manufacturing platforms and fit into manufacturing facilities.
• Perform multivariate process trending analysis to support development and optimization of manufacturing processes for biopharmaceuticals and bioconjugates.
• Model impact of innovative strategies on existing and new manufacturing processes.
• Apply modeling approaches to process development including model transfer learning.
• Provide modeling support for biopharmaceutical process characterization activities in preparation for process validation.
• Evaluate process and cost modeling software applications for use in biopharmaceutical development.
• Collaboration with internal and external groups.
• Represent the Process Development Department on various project teams.
• Develop AI/ML model applications for hybrid models, and the exploration of innovative approaches to model building, including AI/ML techniques.Minimum Requirements/Qualifications:
  • The preferred candidate holds a Ph.D. degree or a M.S. degree in biochemical engineering/biotechnology or closely related fields with 3+ years (PhD.) or 9+ years (M.S.) of experience in modeling and bioprocess development.
  • The open position requires hands-on experience in process modeling applications (such as gProms, GoSilico, BioSolve, SIMCA, etc.).
  • Additional hands-on and lab-based process and/or high-throughput development experience is preferred.
  • You should be familiar with cGMPs for biopharmaceuticals and regulatory submissions and show the ability to work well independently as well as a member of a team.
  • High communication skills, excellent written and verbal communication.
  • Programming skills (e.g. Matlab, Python).
  • Ability to present findings clearly to non-technical stakeholders.
  • Ability to work in fast-paced environments.
  • Teamwork skills for working in a diverse, global environment.
  • Willingness to stay updated with the latest industry trends and technologies.
  • May require approximately 10-20% travel.More about us:At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy.#LI-SB1Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. -For Location:Lexington, MAU.S. Base Salary Range:$133,000.00 - $209,000.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.---The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. -U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. -EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsLexington, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Arlington , Senior Staff Engineer, Modeling, Other , Lexington, Massachusetts